Dr. Megyeri Klára

Email: megyeri.klara@med.u-szeged.hu

Phone: +36 62 545-541

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Research areas

The focus of our research is the effect of bacteria and viruses on cellular and immune processes.

- We study the mechanism of cytopathogenicity triggered by several infections.

- We investigate the various functions of the innate immunity in infections.

- We examine the cellular effects of certain virotherapy agents.

Selected publications:

Orosz L, Papanicolaou EG, Seprényi G, Megyeri K.:
IL-17A and IL-17F induce autophagy in RAW 264.7 macrophages. Biomed Pharmacother. 2016;77:129-34.

Klionsky DJ, Abdelmohsen K, Banhegyi G, Lekli I, Megyeri K, Orosz L, Zughaier SM et al.:
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy 2016;12:1-222.

Petrovski G, Pasztor K, Orosz L, Albert R, Mencel E, Moe MC, Kaarniranta K, Facsko A, Megyeri K.:
Herpes simplex virus types 1 and 2 modulate autophagy in SIRC corneal cells. J Biosci. 2014;39:683-92.

Pásztor K, Orosz L, Seprényi G, Megyeri K.:
Rubella virus perturbs autophagy. Med Microbiol Immunol. 2014;203:323-31.

Megyeri K, Orosz L, Kormos B, Pásztor K, Seprényi G, Ocsovszki I, Mándi Y, Bata-Csörgő Z, Kemény L.:
The herpes simplex virus-induced demise of keratinocytes is associated with a dysregulated pattern of p63 expression. Microbes Infect. 2009;11:785-94.

Megyeri K, Orosz L, Kemény L.:
Vesicular stomatitis virus infection triggers apoptosis associated with decreased DeltaNp63alpha and increased Bax levels in the immortalized HaCaT keratinocyte cell line. Biomed Pharmacother. 2007;61:254-60.

Megyeri K, Berencsi K, Halazonetis TD, Prendergast GC, Gri G, Plotkin SA, Rovera G, Gönczöl E.:
Involvement of a p53-dependent pathway in rubella virus-induced apoptosis. Virology. 1999;259:74-84.

Megyeri K, Au WC, Rosztoczy I, Raj NB, Miller RL, Tomai MA, Pitha PM.:
Stimulation of interferon and cytokine gene expression by imiquimod and stimulation by Sendai virus utilize similar signal transduction pathways. Mol Cell Biol. 1995;15:2207-18.

Rosztoczy I, Content J, Megyeri K.:
Interferon pretreatment regulates interferon and interleukin-6 production in L929 cells in a coordinated manner. J Interferon Res. 1992;12:13-6.